Research Summary

Research Summary

Friday, January 28, 2022

Work Experience And Education

Principal Scientist (Sep 2023—Current) at PTC Therapeutics, NJ 07080, USA

Sr Scientist (March 2020—Aug 2023) at PTC Therapeutics, NJ 07080, USA

Scientist-II (April, 2018—Feb 2020) at PTC Therapeutics, NJ 07080, USA

Postdoctoral Research (September, 2016—March, 2018) with Prof. Gary A Molander at University of Pennsylvania(UPenn), USA

Doctoral Research (Ph. D.): Advisor—Prof. Kálmán Szabó, Stockholm University, Sweden
Ph. D. Examiner: Prof. Varinder K Aggarwal (Bristol University, UK)

To read and download the Doctoral Thesis please click here.

MS (Organic Chemistry): Thesis Advisor—Prof. Kálmán Szabó, Stockholm University, Sweden

BSc (Chemistry): University of Chittagong, Bangladesh. 

Published Books: "একটা দেশ যেভাবে দাঁড়ায়"; "বাংলাদেশের স্বপ্নচোখ"; "সফল মন্ত্র

List of Patents: 

01. WO/2019/191229 Link; Highlighted in ACS. Med. Chem. Lett.
02. WO/2020/005873 LinkHighlighted in ACS. Med. Chem. Lett.
03.  WO/2020/231977 Link
04.  WO/2021/207453 LinkHighlighted in ACS. Med. Chem. Lett.
05.  WO/2023/028536 LinkHighlighted in ACS. Med. Chem. Lett.
06.  WO/2023/028534 Link


List of Scientific Publications: 

13. Photoredox‐Catalyzed Multicomponent Petasis Reaction with Alkyltrifluoroborates
Jun Yi, Shorouk O. Badir, Rauful Alam, and Gary A. Molander. Org. Lett., 2019 (ASEP) (Link)

12. 
Photoredox/Nickel‐Catalyzed Single‐Electron Tsuji‐Trost Reaction: Development and Mechanistic Insight
Jennifer K. Matsui, Álvaro Gutiérrez-Bonet, Madeline Rotella, Rauful Alam, Osvaldo Gutierrez and Gary A. Molander. Angewandte Chemie International Edition, 2018 (ASEP) (Link





11. Photoredox-catalyzed Direct Reductive Amination of Aldehydes without an External Hydrogen/Hydride Source
Rauful Alam and Gary A. Molander. Org. Lett., 2018, 20, 2680-2684 (Link




10. Direct Synthesis of Secondary Benzylic Alcohols Enabled by Photoredox/Ni-Dual Catalysis.
Rauful Alam and Gary A. Molander. J. Org. Chem., 201782,13728–13734 (LinkHighlighted in Synfacts 201814, 0188.



Gram Scale Reaction



09. Synergistic Visible Light Photoredox/Nickel-Catalyzed Synthesis of Aliphatic Ketones via N-C Cleavage of Imides.

Javad Amani, Rauful Alam, Shorouk Badir and Gary A. Molander. Org. Lett, 2017, 19, 2426-2429  (Link) Hilighted in Synfacts 2017, 13, 0742Highlighted in OPR&D 2017, 21, 897-910


One of the ketones



Publications Prior to Postdoctoral Research



08. Catalytic Asymmetric Allylboration of Indoles and Dihydroisoquinolines with Allylboronic Acids: Stereodivergent Synthesis of up to Three Contiguous Stereocenters 

Rauful Alam, Colin Diner, Sybrand Jonker, Lars Eriksson and Kálmán J. Szabó 

Angew. Chem. Int. Ed. 201655, 14417–14421 (Link) Highlighted in ChemistryViewsChemistry world and Synfacts

 
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07. Transition-Metal-Free Borylation of Allylic and Propargylic Alcohols

Núria Miralles, Rauful Alam, Kálmán J. Szabó, Elena Fernández

Angew. Chem. Int. Ed. 2016, 55, 4303–4307 (Link) Highlighted in Cheminform 



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06. Synthesis of Adjacent Quaternary Stereocenters by Catalytic Asymmetric Allylboration

Rauful Alam, Tobias Vollgraff, Lars Eriksson and Kálmán J. Szabó

J. Am. Chem. Soc. 2015, 137, 11262-11265 (Link) Highlighted in Cheminform 



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05. Stereocontrol in Synthesis of Homoallylic Amines. Syn Selective Direct Allylation of Hydrazones with Allylboronic Acids

Arindam Das, Rauful Alam, Lars Eriksson and Kálmán J. Szabó

Org. Lett. 201416, 3808–3811 (Link) Highlighted in Cheminform



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04. Stereoselective allylboration of imines and indoles under mild conditions. An in situ E/isomerization of imines by allylboroxines

Rauful Alam, Arindam Das, Genping Huang, Fahmi Himo, Lars Eriksson and Kálmán J. Szabó
Chem. Sci. 20145, 2732–2738 (Link
Highlighted in Cheminform 



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03. Selective Formation of Adjacent Stereocenters by Allylboration of Ketones under Mild Neutral Conditions

Rauful Alam, Mihai Raducan, Lars Eriksson and Kálmán J. Szabó

Org. Lett. 201315, 2546–2549 (Link

X-ray structure of a compound


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02. Palladium-Catalyzed Synthesis and Isolation of Functionalized Allylboronic Acids: Selective, Direct Allylboration of Ketones

Mihai Raducan, Rauful Alam and Kálmán J. Szabó
Angew. Chem. Int. Ed. 201251, 13050–13053 (LinkHighlighted in Synfacts and ChemInform

Allyl boronic acid






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01. Stereoselective Intermolecular Allylic C–H Trifluoroacetoxylation of Functionalized Alkenes

Rauful Alam, Lukasz T. Pilarski, Elias Pershagen, and Kálmán J. Szabó

J. Am. Chem. Soc.2012134, 8778–8781 (LinkHighlighted in ChemInform




Scholarships/Awards: 

08. Bengt Lundqvist Postdoctoral Scholarship—2016 through Swedish Chemical Society.


07. Sture Erikssons Scholarship to attend 
PACIFICHEM-2015 at Hawaii, USA

06. Stiftelsen Sigrud och Elsa Goljes Memmorial Scholarship-2015.


05. Knut och Alice Wallenbergs Scholarship, 2014

04. The Royal Swedish Academy of Sciences travel grant, 2014

03. Stiftelsen Sigrud och Elsa Goljes Memmorial Scholarship, 2013

02. C F Liljevalchs J:ors stipend, 2012

01. Ångpanneföreningens Forskningsstiftelse stipend, 2012


Scientific Lectures and Presentations: 


09.  4th Silk Road International Symposium for Distinguished Young Scholars (SRIS-2018)—April 2018 (Xi'an, China): Oral Presentation. 

08. 254th ACS National Meeting and Exposition—August 2017 (Washington, USA): Oral and Poster Presentation. Presentation in Sci-Mix session. Link

07. PACIFICHEM (The International Chemical Congress of Pacific Basin Societies)—December 2015 (Hawaii, USA): Oral and Poster presentation.

06. OMCOS (Organometallic Chemistry Directed Towards Organic Synthesis)—June 2015 (Sitges, Spain): Poster presentation


05. CARISMA (Catalytic Routines for Small Molecule Activation) Meeting—March 2015 (Tarragona, Spain): Poster presentation


04. Organikerdagarna—June 2014 (Djurönäset, Stockholm): Oral Presentation


03. 248th ACS National Meeting and Exposition—August 2014 (San Francisco, USA): Oral and Poster Presentation. Presentation in Sci-Mix session.

02. 246th ACS National Meeting and Exposition—September 2013 (Indianapolis, USA): Oral and Poster Presentation. Presentation in Sci-Mix session.

01. 244th ACS National Meeting and Exposition—August 2012 (Philadelphia, USA): 
Oral and Poster Presentation. Presentation in Sci-Mix session.